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That decline tracks closely with loss of skin elasticity, slower wound healing, and the general deterioration of tissue quality that people associate with aging

Even a slight imbalance can cause symptoms that affect daily life

This approach aligns well with the nature of autoimmune conditions where the fundamental problem is regulatory failure

Sci Rep 6 , 30033 (2016)

Additionally, while both microvascular complications and cardiovascular disease prone to occur more frequently with longer diabetes duration, the impact of diabetes duration on cardiovascular disease is less severe than that on microvascular complications [2]